Fung Lung Chung

Formation of cyclic 1,N2-propanodeoxyguanosine adducts in DNA upon reaction with acrolein or crotonaldehyde.

Fung Lung Chung, Ruth Young, Stephen S. Hecht · PubMed · 1984 · 300 citations

Pharmacy, Biochemistry, Molecular Biology +15

Effects of aromatic isothiocyanates on tumorigenicity, O6-methylguanine formation, and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung.

Mark A. Morse, Shantu Amin, Stephen S. Hecht et al. · PubMed · 1989 · 182 citations

Medicine, Oncology, Pharmacology +12

Deoxyguanosine adducts of t-4-hydroxy-2-nonenal are endogenous DNA lesions in rodents and humans: detection and potential sources.

Fung Lung Chung, Raghu G. Nath, Joseph E. Ocando et al. · PubMed · 2000 · 154 citations

Pharmacy, Biochemistry, Toxicology +17

Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice.

Mark A. Morse, S D LaGreca, Shantu Amin et al. · PubMed · 1990 · 150 citations

Medicine, Oncology, Pharmacology +14

Structure-activity relationships for inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice.

Mark A. Morse, Karin I. Eklind, Stephen S. Hecht et al. · PubMed · 1991 · 137 citations

Medicine, Pharmacology, Toxicology +10