Shantu Amin

Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.

Tsutomu Shimada, Carrie L. Hayes, Hiroshi Yamazaki et al. · PubMed · 1996 · 795 citations

Chemoprevention Strategy, Escherichia Coli, Chemical Biology +17

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

Changtao Jiang, Cen Xie, Fei Li et al. · Journal of Clinical Investigation · 2014 · 655 citations · Full text

Gastroenterology, Pathology, Gut Microbiota +16

Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction

Changtao Jiang, Cen Xie, Ying Lv et al. · Nature Communications · 2015 · 529 citations · Full text

Autophagosomal Membrane Serves as Platform for Intracellular Death-inducing Signaling Complex (iDISC)-mediated Caspase-8 Activation and Apoptosis

Megan M. Young, Yoshinori Takahashi, Osman Khan et al. · Journal of Biological Chemistry · 2012 · 355 citations · Full text

Mitophagy, Caspase Cascade, Apoptosis +18

Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles

Troy D. Hubbard, Iain A. Murray, William H. Bisson et al. · Scientific Reports · 2015 · 351 citations · Full text