Tiziana Scoccitti

B(C₆F₅)₃-Catalyzed Hydrosilation of Imines via Silyliminium Intermediates

James M. Blackwell, Eric R. Sonmor, Tiziana Scoccitti et al. · Organic Letters · 2000 · 344 citations

Inorganic Chemistry, Chemical Engineering, Engineering +10

The discovery of 6-[2-(5-chloro-2-{[(2,4-difluorophenyl)methyl]oxy}phenyl)-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid, GW848687X, a potent and selective prostaglandin EP1 receptor antagonist for the treatment of inflammatory pain

Gerard M.P. Giblin, Rino A. Bit, Susan H. Brown et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 47 citations · Full text

Inflammation, Medicinal Chemistry, Anti-inflammatory +13

Identification of 2-oxo-N-(phenylmethyl)-4-imidazolidinecarboxamide antagonists of the P2X7 receptor

Lee Abberley, Aude Bebius, Paul Beswick et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 29 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +8

Discovery of a novel indole series of EP1 receptor antagonists by scaffold hopping

Adrian Hall, Andy Billinton, Susan H. Brown et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 27 citations · Full text

Medicinal Chemistry, Drug Target, Scaffold Hopping +11

Discovery of GSK345931A: An EP1 receptor antagonist with efficacy in preclinical models of inflammatory pain

Adrian Hall, Susan H. Brown, Nicholas M. Clayton et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 27 citations · Full text

Inflammation, Molecular Pharmacology, Anti-inflammatory +15