Philippe Cluzeau

Structure-based design and synthesis of novel non-zinc chelating MMP-12 inhibitors

Anne‐Claude Dublanchet, Pierre Ducrot, Charles R. Andrianjara et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 69 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Natural Sciences +7

Discovery of 1,4-Disubstituted 3-Cyano-2-pyridones: A New Class of Positive Allosteric Modulators of the Metabotropic Glutamate 2 Receptor

José M. Cid, Guillaume Duvey, Gary Tresadern et al. · Journal of Medicinal Chemistry · 2012 · 34 citations · Full text

Discovery of 1,5-Disubstituted Pyridones: A New Class of Positive Allosteric Modulators of the Metabotropic Glutamate 2 Receptor

José M. Cid, Guillaume Duvey, Philippe Cluzeau et al. · ACS Chemical Neuroscience · 2010 · 25 citations

Compound 8, High Throughput, Locomotor Activity +19

New positive allosteric modulators of the metabotropic glutamate receptor 2 (mGluR2): Identification and synthesis of N-propyl-8-chloro-6-substituted isoquinolones

Andrés A. Trabanco, Guillaume Duvey, José M. Cid et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 19 citations · Full text

Molecular Pharmacology, Biochemistry, Functional Selectivity +6

New positive allosteric modulators of the metabotropic glutamate receptor 2 (mGluR2). Identification and synthesis of N-propyl-5-substituted isoquinolones

Andrés A. Trabanco, Guillaume Duvey, José M. Cid et al. · MedChemComm · 2010 · 10 citations

Molecular Pharmacology, Medicinal Chemistry, Derivative (Chemistry) +15