Leonard Petrucelli

Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS

Peter E.A. Ash, Kevin F. Bieniek, Tania F. Gendron et al. · Neuron · 2013 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +7

RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention

Christopher J. Donnelly, Ping‐Wu Zhang, Jacqueline T. Pham et al. · Neuron · 2013 · 882 citations

Life Sciences, Molecular Biology, Neuroscience +16

GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport

Brian D. Freibaum, Yubing Lu, Nam Chul Kim et al. · Nature · 2015 · 870 citations

Life Sciences, Genetics, Molecular Biology +9

CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation

Leonard Petrucelli · Human Molecular Genetics · 2004 · 725 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a <i>C9ORF72</i> Repeat Expansion

Dhruv Sareen, Jacqueline G. O’Rourke, Pratap Meera et al. · Science Translational Medicine · 2013 · 691 citations · Full text

Life Sciences, Genetics, Neuroscience +17