Nicole P. Kasica

Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity, and memory in mouse models of Alzheimer’s disease

Maurício M. Oliveira, Mychael V. Lourenco, Francesco Longo et al. · Science Signaling · 2021 · 138 citations · Full text

Genetic reduction of eEF2 kinase alleviates pathophysiology in Alzheimer’s disease model mice

Brenna C. Beckelman, Wenzhong Yang, Nicole P. Kasica et al. · Journal of Clinical Investigation · 2019 · 126 citations · Full text

Eef2 Kinase, Synaptic Transmission, Synaptic Signaling +19

Brain-specific repression of AMPKα1 alleviates pathophysiology in Alzheimer’s model mice

Helena R. Zimmermann, Wenzhong Yang, Nicole P. Kasica et al. · Journal of Clinical Investigation · 2020 · 91 citations · Full text

Mammalian Ampk, Ampkα Isoforms, Brain-specific Repression +18

Antagonists targeting eEF2 kinase rescue multiple aspects of pathophysiology in Alzheimer’s disease model mice

Nicole P. Kasica, Xueyan Zhou, Qian Yang et al. · Journal of Neurochemistry · 2021 · 36 citations · Full text

Impaired Mrna Translation, Synaptic Transmission, Alzheimer ’ +19

Genetic removal of <scp>eIF</scp>2α kinase <scp>PERK</scp> in mice enables hippocampal L‐<scp>LTP</scp> independent of <scp>mTORC</scp>1 activity

Helena R. Zimmermann, Wenzhong Yang, Brenna C. Beckelman et al. · Journal of Neurochemistry · 2018 · 23 citations · Full text

Synaptic Transmission, Rapamycin Complex 1, Rapamycin-induced L-ltp Failure +23