Concepedia

Naoto Hirano

NH

66

Publications

5.8K

Citations

36

H-Index

1989

Active since

Affiliations

University of Toronto(Current)

Princess Margaret Cancer Centre

University Health Network

Dana-Farber Cancer Institute

Brigham and Women's Hospital

Naoto Hirano is an author at University of Toronto specializing in medicine, immunology, and cell biology.

Top concepts

MedicineImmunologyAutoimmunityCell BiologyImmunotherapyCell SignalingAutoimmune DiseaseTumor ImmunityT Cell ImmunitySignal Transduction

Publications per year

1989–2024

66

Publications

66

A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner.

Ryuichi Sakai, Akihiro Iwamatsu, Naoto Hirano et al. · The EMBO Journal · 1994 · 653 citations · Full text

A novel chimeric antigen receptor containing a JAK–STAT signaling domain mediates superior antitumor effects

Yuki Kagoya, Shinya Tanaka, Tingxi Guo et al. · Nature Medicine · 2018 · 560 citations

Immunology, Tumor Immunity, Immunoediting +6

Transplantation of Anergic Histoincompatible Bone Marrow Allografts

Eva C. Guinan, Vassiliki A. Boussiotis, Donna Neuberg et al. · New England Journal of Medicine · 1999 · 435 citations

Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells

Dimitrios Tzachanis, Gordon J. Freeman, Naoto Hirano et al. · Nature Immunology · 2001 · 274 citations

Signal Transduction, Negative Regulator, T-regulatory Cell +9

BET bromodomain inhibition enhances T cell persistence and function in adoptive immunotherapy models

Yuki Kagoya, Munehide Nakatsugawa, Yūki Yamashita et al. · Journal of Clinical Investigation · 2016 · 210 citations · Full text

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