Vassiliki A. Boussiotis

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

Yvette Latchman, Clive R. Wood, Tatyana Chernova et al. · Nature Immunology · 2001 · 2.9K citations

Cancer Immunosurveillance, Signal Transduction, Immunology +8

PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation

Nikolaos Patsoukis, Kankana Bardhan, Pranam Chatterjee et al. · Nature Communications · 2015 · 1.1K citations · Full text

Immunology, Metabolic Remodeling, Fatty Acid Oxidation +19

Cloning of B7-2: a CTLA-4 Counter-Receptor That Costimulates Human T Cell Proliferation

Gordon J. Freeman, John G. Gribben, Vassiliki A. Boussiotis et al. · Science · 1993 · 911 citations

Lymphocyte Development, T-regulatory Cell, Immunology +16

B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4

Gordon J. Freeman, Vassiliki A. Boussiotis, Anukanth Anumanthan et al. · Immunity · 1995 · 565 citations · Full text

Initial Production, Immunology, Autoimmunity +3

Selective Effects of PD-1 on Akt and Ras Pathways Regulate Molecular Components of the Cell Cycle and Inhibit T Cell Proliferation

Nikolaos Patsoukis, Julia A. Brown, Victoria Petkova et al. · Science Signaling · 2012 · 506 citations · Full text