Concepedia
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Publications
87
Citations
7.8K
H-Index
43
Active since
1988
Affiliations
The University of Tokyo(Current)
National Cancer Research Institute
Kitasato University
Jichi Medical University
National Cancer Centre Japan
Ryuichi Sakai is an author at The University of Tokyo specializing in medicine, cell biology, and tumor biology.
Top concepts
MedicineCell BiologyTumor BiologyCell SignalingCancer ResearchSignal TransductionPathologyCancer BiologyCell PhysiologyCellular Biochemistry
Publications per year
1988–2022
Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas
Yasuhiro Sawada, Masako Tamada, Benjamin J. Dubin‐Thaler et al. · Cell · 2006 · 927 citations · Full text
Mechanobiology, Mechanical Extension, Signal Transduction +10
A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner.
Ryuichi Sakai, Akihiro Iwamatsu, Naoto Hirano et al. · The EMBO Journal · 1994 · 653 citations · Full text
Mammalian Grb2 Regulates Multiple Steps in Embryonic Development and Malignant Transformation
Alec M. Cheng, Tracy M. Saxton, Ryuichi Sakai et al. · Cell · 1998 · 377 citations · Full text
Developmental Biology, Malignant Transformation, Morphogenesis +7
Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas
Hiroaki Honda, Hideaki Oda, Tetsuya Nakamoto et al. · Nature Genetics · 1998 · 361 citations
Knockout Mouse, Signal Transduction, Mice Lacking P130cas +11
Integrin-mediated Cell Adhesion Promotes Tyrosine Phosphorylation of p130Cas, a Src Homology 3-containing Molecule Having Multiple Src Homology 2-binding Motifs
Yoshihisa Nojima, Noritsugu Morino, Toshihide Mimura et al. · Journal of Biological Chemistry · 1995 · 335 citations · Full text
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