Adrian Roth

Bioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In Vitro

Deborah G. Nguyen, Juergen Funk, Justin B. Robbins et al. · PLoS ONE · 2016 · 366 citations · Full text

Tissue Engineering, Engineering, Biofabrication +24

Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes

Sebastiaan J. Trietsch, Elena Naumovska, Dorota Kurek et al. · Nature Communications · 2017 · 283 citations · Full text

A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity

Radina Kostadinova, Franziska Boess, Dawn Applegate et al. · Toxicology and Applied Pharmacology · 2013 · 257 citations

Translational Medicine, Hepatology, Medicine +15

Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics

Christopher W. McAleer, Christopher J. Long, Daniel Elbrecht et al. · Science Translational Medicine · 2019 · 169 citations

Oncology, Off-target Toxicity, Multi-organ System +15

Regulatory Cross-Talk between Drug Metabolism and Lipid Homeostasis: Constitutive Androstane Receptor and Pregnane X Receptor Increase Insig-1 Expression

Adrian Roth, Renate Looser, Michel Kaufmann et al. · Molecular Pharmacology · 2008 · 141 citations