Christopher W. McAleer

Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics

Christopher W. McAleer, Christopher J. Long, Daniel Elbrecht et al. · Science Translational Medicine · 2019 · 169 citations

Oncology, Off-target Toxicity, Multi-organ System +15

Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system

Carlota Oleaga, Anne Riu, Sandra Rothemund et al. · Biomaterials · 2018 · 161 citations

Cardiovascular Toxicity, Off-target Cardiotoxicity, Hepatology +15

Stem cell derived phenotypic human neuromuscular junction model for dose response evaluation of therapeutics

Navaneetha Santhanam, Lee Kumanchik, Xiufang Guo et al. · Biomaterials · 2018 · 115 citations

Regenerative Medicine, Cell Therapy, Medicine +8

Differential Monocyte Actuation in a Three‐Organ Functional Innate Immune System‐on‐a‐Chip

Trevor Sasserath, John W. Rumsey, Christopher W. McAleer et al. · Advanced Science · 2020 · 88 citations · Full text

On the potential of in vitro organ-chip models to define temporal pharmacokinetic-pharmacodynamic relationships

Christopher W. McAleer, Amy Pointon, Christopher J. Long et al. · Scientific Reports · 2019 · 87 citations · Full text

Quantitative Translation, Pharmacotherapy, Biomedical Engineering +20