Mary C. Wheldon

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission

David A. Baker, Lindsay B. Stewart, Jonathan M. Large et al. · Nature Communications · 2017 · 185 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Design and Synthesis of 56 Shape‐Diverse 3D Fragments

Thomas D. Downes, Simon Jones, Hanna F. Klein et al. · Chemistry - A European Journal · 2020 · 60 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG)

Denise J. Tsagris, Kristian Birchall, Nathalie Bouloc et al. · Bioorganic & Medicinal Chemistry Letters · 2018 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Lead-oriented synthesis: Investigation of organolithium-mediated routes to 3-D scaffolds and 3-D shape analysis of a virtual lead-like library

Monique Lüthy, Mary C. Wheldon, Chehasnah Haji-Cheteh et al. · Bioorganic & Medicinal Chemistry · 2015 · 26 citations

Pharmacy, Chemistry, Medicinal Chemistry +16

Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines

Jonathan M. Large, Kristian Birchall, Nathalie Bouloc et al. · Bioorganic & Medicinal Chemistry Letters · 2018 · 19 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14