Kristian Birchall

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission

David A. Baker, Lindsay B. Stewart, Jonathan M. Large et al. · Nature Communications · 2017 · 185 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay

Juan Guzman, Dimitrios Evangelopoulos, Antima Gupta et al. · BMJ Open · 2013 · 94 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo PHD Finger

Thomas C. R. Miller, Trevor J. Rutherford, Kristian Birchall et al. · ACS Chemical Biology · 2014 · 64 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches

Patrick J. McIntyre, P.M. Collins, Lukáš Vrzal et al. · ACS Chemical Biology · 2017 · 57 citations

Life Sciences, Molecular Biology, Oncology +17

Substituted imidazopyridazines are potent and selective inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1)

Timothy M. Chapman, Simon A. Osborne, Nathalie Bouloc et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17