Kristian Birchall

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission

David A. Baker, Lindsay B. Stewart, Jonathan M. Large et al. · Nature Communications · 2017 · 173 citations · Full text

Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay

Juan Guzman, Dimitrios Evangelopoulos, Antima Gupta et al. · BMJ Open · 2013 · 92 citations · Full text

Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo PHD Finger

Thomas C. R. Miller, Trevor J. Rutherford, Kristian Birchall et al. · ACS Chemical Biology · 2014 · 64 citations · Full text

Molecular Biology, Pygo-bcl9 Complex, Histone-binding Pocket +20

Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches

Patrick J. McIntyre, P.M. Collins, Lukáš Vrzal et al. · ACS Chemical Biology · 2017 · 54 citations

Molecular Biology, Tumor Biology, Mitotic Kinase Aurora-a +23

Substituted imidazopyridazines are potent and selective inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1)

Timothy M. Chapman, Simon A. Osborne, Nathalie Bouloc et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 53 citations · Full text

Vitro Adme, Antiparasitic Agent, Malaria +16