Denise J. Tsagris

Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG)

Denise J. Tsagris, Kristian Birchall, Nathalie Bouloc et al. · Bioorganic & Medicinal Chemistry Letters · 2018 · 27 citations · Full text

Medicinal Chemistry, Biochemistry, Antiparasitic Agent +9

Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines

Jonathan M. Large, Kristian Birchall, Nathalie Bouloc et al. · Bioorganic & Medicinal Chemistry Letters · 2018 · 19 citations · Full text

Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty

Jonathan M. Large, Kristian Birchall, Nathalie Bouloc et al. · Bioorganic & Medicinal Chemistry Letters · 2019 · 17 citations · Full text

Discovery of potent and selective 5-azaindazole inhibitors of leucine-rich repeat kinase 2 (LRRK2) – Part 1

Joanne Osborne, Kristian Birchall, Denise J. Tsagris et al. · Bioorganic & Medicinal Chemistry Letters · 2018 · 16 citations · Full text