Sheue-Houy Tyan

Amyloid precursor protein (APP) regulates synaptic structure and function

Sheue-Houy Tyan, Ann Shih, Jessica J. Walsh et al. · Molecular and Cellular Neuroscience · 2012 · 179 citations · Full text

Neurodegenerative Diseases, Synaptic Plasticity, Molecular Neuroscience +7

Caspase Activation and Caspase-Mediated Cleavage of APP Is Associated with Amyloid β-Protein-Induced Synapse Loss in Alzheimer’s Disease

Goonho Park, Hoang S. Nhan, Sheue-Houy Tyan et al. · Cell Reports · 2020 · 87 citations · Full text

Synaptic Transmission, Cell Death, Neurochemical Biomarkers +28

The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy

Wan Yun Ho, Yee Kit Tai, Jer‐Cherng Chang et al. · Autophagy · 2019 · 66 citations · Full text

Cell Autophagy, Neurodegenerative Diseases, Mitophagy +15

Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function

Brea Midthune, Sheue-Houy Tyan, Jessica J. Walsh et al. · Molecular and Cellular Neuroscience · 2012 · 35 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Molecular Neuroscience +8

Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits

Wan Yun Ho, Ira Agrawal, Sheue-Houy Tyan et al. · Acta Neuropathologica Communications · 2021 · 27 citations · Full text