Paul K. Spearing

A New Series of Estrogen Receptor Modulators That Display Selectivity for Estrogen Receptor β

Brad R. Henke, Thomas G. Consler, Ning Go et al. · Journal of Medicinal Chemistry · 2002 · 159 citations · Full text

Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064

Adwoa Akwabi-Ameyaw, Jonathan Y. Bass, Richard D. Caldwell et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 137 citations · Full text

Naphthoic Acid-based Analogs, Biochemistry, G Protein-coupled Receptor +12

Discovery of Tertiary Sulfonamides as Potent Liver X Receptor Antagonists

William J. Zuercher, Richard G. Buckholz, Nino Campobasso et al. · Journal of Medicinal Chemistry · 2010 · 94 citations · Full text

Pharmaceutical Science, Tertiary Sulfonamide Series, Molecular Biology +17

FXR agonist activity of conformationally constrained analogs of GW 4064

Adwoa Akwabi-Ameyaw, Jonathan Y. Bass, Richard D. Caldwell et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 61 citations · Full text

G Protein-coupled Receptor, Functional Selectivity, Molecular Biology +4

Conformationally constrained farnesoid X receptor (FXR) agonists: Heteroaryl replacements of the naphthalene

Jonathan Y. Bass, Justin A. Caravella, Lihong Chen et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 60 citations · Full text

Drug Target, Functional Selectivity, Medicine +8