Lihong Chen

Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage

Chuangui Wang, Lihong Chen, Xinghua Hou et al. · Nature Cell Biology · 2006 · 442 citations

Reductive Stress, Chromatin, Genome Instability +10

Timing of expression of the core clock gene <i>Bmal1</i> influences its effects on aging and survival

Guangrui Yang, Lihong Chen, Gregory R. Grant et al. · Science Translational Medicine · 2016 · 313 citations · Full text

Transcriptional Regulation, Aging, Core Clock Gene +15

Circadian control of innate immunity in macrophages by miR-155 targeting <i>Bmal1</i>

Annie M. Curtis, Caio T. Fagundes, Guangrui Yang et al. · Proceedings of the National Academy of Sciences · 2015 · 294 citations · Full text

Innate Immune System, Immunology, Immune Regulation +23

Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064

Adwoa Akwabi-Ameyaw, Jonathan Y. Bass, Richard D. Caldwell et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 137 citations · Full text

Naphthoic Acid-based Analogs, Biochemistry, G Protein-coupled Receptor +12

Activation of p53 by roscovitine-mediated suppression of MDM2 expression

Wenge Lu, Lihong Chen, Yanhua Peng et al. · Oncogene · 2001 · 119 citations

Oncogenic Agent, Mdm2 Expression, Tumor Suppressor +4