Alan Opsahl

Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice

Emily Cokorinos, Jake Delmore, Allan R. Reyes et al. · Cell Metabolism · 2017 · 259 citations · Full text

Metabolic Syndrome, Muscle Physiology, Muscle Function +15

Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models

Ryan M. Esquejo, Christopher T. Salatto, Jake Delmore et al. · EBioMedicine · 2018 · 146 citations · Full text

Pentamidine reduces <i>hERG</i> expression to prolong the QT interval

Jason Cordes, Zhuoqian Sun, David B. Lloyd et al. · British Journal of Pharmacology · 2005 · 128 citations · Full text

Molecular Pharmacology, Translational Medicine, Antiprotozoal Agent +15

A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys

Michael St. Andre, M. Catherine Johnson, Prashant Bansal et al. · Skeletal Muscle · 2017 · 98 citations · Full text

Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems

Trenton T. Ross, Collin Crowley, Kenneth L. Kelly et al. · Cellular and Molecular Gastroenterology and Hepatology · 2020 · 89 citations · Full text