Wijnand J. C. van der Velden

Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist

Francis S. Willard, Jonathan D. Douros, M Gabe et al. · JCI Insight · 2020 · 487 citations · Full text

Medicine, Endocrinology, Pharmacology +17

Structural basis of odorant recognition by a human odorant receptor

Christian B. Billesbølle, Claire A. de March, Wijnand J. C. van der Velden et al. · Nature · 2023 · 227 citations · Full text

Life Sciences, Neuroscience, Physiology +16

A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor

Wen Sun, Li-Nan Chen, Qingtong Zhou et al. · Cell Research · 2020 · 66 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17

Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long‐term impairment of the GIP system

M Gabe, Wijnand J. C. van der Velden, Sarina Gadgaard et al. · Basic & Clinical Pharmacology & Toxicology · 2019 · 52 citations · Full text

Medicine, Endocrinology, Pharmacology +17

Pyrrolone Derivatives as Intracellular Allosteric Modulators for Chemokine Receptors: Selective and Dual-Targeting Inhibitors of CC Chemokine Receptors 1 and 2

Natalia V. Ortiz Zacarı́as, Jacobus P. D. van Veldhoven, Laura Portner et al. · Journal of Medicinal Chemistry · 2018 · 43 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17