Natalia V. Ortiz Zacarı́as

Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists

Yi Zheng, Ling Qin, Natalia V. Ortiz Zacarı́as et al. · Nature · 2016 · 296 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function

Arnault Massink, Hugo Gutiérrez‐de‐Terán, Eelke B. Lenselink et al. · Molecular Pharmacology · 2014 · 100 citations · Full text

Medicine, Molecular Biology, Pharmacology +17

A novel CCR2 antagonist inhibits atherogenesis in apoE deficient mice by achieving high receptor occupancy

Ilze Bot, Natalia V. Ortiz Zacarı́as, Wilhelmus E. A. de Witte et al. · Scientific Reports · 2017 · 66 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Pyrrolone Derivatives as Intracellular Allosteric Modulators for Chemokine Receptors: Selective and Dual-Targeting Inhibitors of CC Chemokine Receptors 1 and 2

Natalia V. Ortiz Zacarı́as, Jacobus P. D. van Veldhoven, Laura Portner et al. · Journal of Medicinal Chemistry · 2018 · 43 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Design and Characterization of an Intracellular Covalent Ligand for CC Chemokine Receptor 2

Natalia V. Ortiz Zacarı́as, Kirti Kandhwal Chahal, Tereza Šimková et al. · Journal of Medicinal Chemistry · 2021 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17