Concepedia

Wilhelmus E. A. de Witte

WE

6

Publications

176

Citations

6

H-Index

2011

Active since

Affiliations

Leiden University(Current)

Centre for Human Drug Research

Fraunhofer Institute for Molecular Biology and Applied Ecology

Wilhelmus E. A. de Witte is an author at Leiden University specializing in glycobiology, natural sciences, and biosynthesis.

ORCID

Top concepts

Publications per year

2011–2018

6

Publications

6

A novel CCR2 antagonist inhibits atherogenesis in apoE deficient mice by achieving high receptor occupancy

Ilze Bot, Natalia V. Ortiz Zacarı́as, Wilhelmus E. A. de Witte et al. · Scientific Reports · 2017 · 64 citations · Full text

Mannopyranosyl Uronic Acid Donor Reactivity

Marthe T. C. Walvoort, Wilhelmus E. A. de Witte, Jesse van Dijk et al. · Organic Letters · 2011 · 41 citations

, , +11

The influence of drug distribution and drug-target binding on target occupancy: The rate-limiting step approximation

Wilhelmus E. A. de Witte, Georges Vauquelin, Piet H. van der Graaf et al. · European Journal of Pharmaceutical Sciences · 2017 · 27 citations · Full text

Target and Tissue Selectivity Prediction by Integrated Mechanistic Pharmacokinetic-Target Binding and Quantitative Structure Activity Modeling

Anna Hendrika Cornelia Vlot, Wilhelmus E. A. de Witte, Meindert Danhof et al. · The AAPS Journal · 2017 · 19 citations · Full text

<i>In vitro</i>and<i>in silico</i>analysis of the effects of<scp>D</scp><sub>2</sub>receptor antagonist target binding kinetics on the cellular response to fluctuating dopamine concentrations

Wilhelmus E. A. de Witte, Joost W Versfelt, Maria Kuzikov et al. · British Journal of Pharmacology · 2018 · 15 citations · Full text

Rows per page

1–5 of 6