Jonathan D. Douros

Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist

Francis S. Willard, Jonathan D. Douros, M Gabe et al. · JCI Insight · 2020 · 439 citations · Full text

Pharmacotherapy, Experimental Pharmacology, Insulin Signaling +20

SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion

Kristin A. Anderson, Frank K. Huynh, Kelsey H. Fisher‐Wellman et al. · Cell Metabolism · 2017 · 319 citations · Full text

Biochemistry, Controls Leucine Metabolism, Diabetes +8

Next generation GLP-1/GIP/glucagon triple agonists normalize body weight in obese mice

Patrick J. Knerr, Stephanie A. Mowery, Jonathan D. Douros et al. · Molecular Metabolism · 2022 · 123 citations · Full text

The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets

Kimberley El, Jonathan D. Douros, Francis S. Willard et al. · Nature Metabolism · 2023 · 102 citations · Full text

Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice

Arkadiusz Liśkiewicz, Ahmed Khalil, Daniela Liśkiewicz et al. · Nature Metabolism · 2023 · 82 citations · Full text