Keith Pitts

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

Till Maurer, Lindsay S. Garrenton, Angela Oh et al. · Proceedings of the National Academy of Sciences · 2012 · 621 citations · Full text

Distinct Pocket, Molecular Biology, Ras Gene +21

A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation

Peter V.N. Bodine, Barbara Stauffer, Helga Ponce‐de‐Leon et al. · Bone · 2009 · 124 citations

Sclerostin, Signal Transduction, Bone Morphogenic Protein +12

Identification of substituted 2-thio-6-oxo-1,6-dihydropyrimidines as inhibitors of human lactate dehydrogenase

Peter S. Dragovich, Benjamin P. Fauber, Laura Corson et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 90 citations · Full text

Aldehyde Dehydrogenase, Human Lactate Dehydrogenase, Biochemistry +6

Bacterial Oxidation of Mercury Metal Vapor, Hg(0)

Tracy Smith, Keith Pitts, Jeffery A. McGarvey et al. · Applied and Environmental Microbiology · 1998 · 86 citations · Full text

Potent α-Synuclein Aggregation Inhibitors, Identified by High-Throughput Screening, Mainly Target the Monomeric State

Martin Kurnik, Cagla Sahin, Camilla Andersen et al. · Cell chemical biology · 2018 · 85 citations

Neurodegenerative Diseases, Drug Target, Biochemistry +7