J. Alex Parker

Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons

J. Alex Parker, Margarita Arango, Salima Abderrahmane et al. · Nature Genetics · 2005 · 510 citations

Molecular Neuroscience, Mammalian Neurons, Medicine +9

C. elegans neurons jettison protein aggregates and mitochondria under neurotoxic stress

Ilija Melentijevic, Márton L. Tóth, Meghan Lee Arnold et al. · Nature · 2017 · 447 citations · Full text

Mitophagy, Neurodegenerative Diseases, Molecular Neuroscience +10

Expanded polyglutamines in <i>Caenorhabditis elegans</i> cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death

J. Alex Parker, John B. Connolly, Cheryl L. Wellington et al. · Proceedings of the National Academy of Sciences · 2001 · 213 citations · Full text

Deletion of C9ORF72 Results in Motor Neuron Degeneration and Stress Sensitivity in C. elegans

Martine Therrien, Guy A. Rouleau, Patrick A. Dion et al. · PLoS ONE · 2013 · 180 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Molecular Neuroscience +15

G3BP1 promotes stress-induced RNA granule interactions to preserve polyadenylated mRNA

Anaïs Aulas, Guillaume Caron, Christos G. Gkogkas et al. · The Journal of Cell Biology · 2015 · 135 citations · Full text