Meghan Lee Arnold

C. elegans neurons jettison protein aggregates and mitochondria under neurotoxic stress

Ilija Melentijevic, Márton L. Tóth, Meghan Lee Arnold et al. · Nature · 2017 · 447 citations · Full text

Mitophagy, Neurodegenerative Diseases, Molecular Neuroscience +10

Stress increases in exopher-mediated neuronal extrusion require lipid biosynthesis, FGF, and EGF RAS/MAPK signaling

Jason Cooper, Ryan Guasp, Meghan Lee Arnold et al. · Proceedings of the National Academy of Sciences · 2021 · 51 citations · Full text

Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early-acting autophagy genes in C. elegans neurons

Yongzhi Yang, Meghan Lee Arnold, Caitlin M. Lange et al. · Nature Aging · 2024 · 46 citations · Full text

Cell Autophagy, Mitophagy, Molecular Neuroscience +11

Large vesicle extrusions from C. elegans neurons are consumed and stimulated by glial-like phagocytosis activity of the neighboring cell

Yu Wang, Meghan Lee Arnold, Anna J Smart et al. · eLife · 2023 · 32 citations · Full text

Quantitative Approaches for Scoring <em>in vivo</em> Neuronal Aggregate and Organelle Extrusion in Large Exopher Vesicles in <em>C. elegans</em>

Meghan Lee Arnold, Jason Cooper, Barth D. Grant et al. · Journal of Visualized Experiments · 2020 · 27 citations · Full text

Mitochondrial Dysfunction, Extracellular Microvesicles, Synaptic Signaling +22