Martine Therrien

Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation

Hyeseung Lee, Robert J. Fenster, S. Sebastian Pineda et al. · Neuron · 2020 · 298 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Imatinib mesylate (STI571) for treatment of children with Philadelphia chromosome-positive leukemia: results from a Children's Oncology Group phase 1 study

Martin Champagne, Renaud Capdeville, Mark Krailo et al. · Blood · 2004 · 238 citations

Medicine, Hematology, Oncology +11

Early Alzheimer’s disease pathology in human cortex involves transient cell states

Vahid Gazestani, Tushar Kamath, Naeem Nadaf et al. · Cell · 2023 · 208 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Deletion of C9ORF72 Results in Motor Neuron Degeneration and Stress Sensitivity in C. elegans

Martine Therrien, Guy A. Rouleau, Patrick A. Dion et al. · PLoS ONE · 2013 · 183 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro

Michael-John Dolan, Martine Therrien, Saša Jereb et al. · Nature Immunology · 2023 · 151 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17