Martine Therrien

Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation

Hyeseung Lee, Robert J. Fenster, S. Sebastian Pineda et al. · Neuron · 2020 · 280 citations · Full text

Molecular Neuroscience, Mitochondrial Biogenesis, Mitochondrial Function +8

Imatinib mesylate (STI571) for treatment of children with Philadelphia chromosome-positive leukemia: results from a Children's Oncology Group phase 1 study

Martin Champagne, Renaud Capdeville, Mark Krailo et al. · Blood · 2004 · 236 citations

Early Alzheimer’s disease pathology in human cortex involves transient cell states

Vahid Gazestani, Tushar Kamath, Naeem Nadaf et al. · Cell · 2023 · 181 citations · Full text

Neurodegenerative Diseases, Human Cortex, Alzheimer's Disease +9

Deletion of C9ORF72 Results in Motor Neuron Degeneration and Stress Sensitivity in C. elegans

Martine Therrien, Guy A. Rouleau, Patrick A. Dion et al. · PLoS ONE · 2013 · 180 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Molecular Neuroscience +15

Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro

Michael-John Dolan, Martine Therrien, Saša Jereb et al. · Nature Immunology · 2023 · 136 citations · Full text