S. Sebastian Pineda

Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation

Hyeseung Lee, Robert J. Fenster, S. Sebastian Pineda et al. · Neuron · 2020 · 298 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity

Mary H. Wertz, Mollie R. Mitchem, S. Sebastian Pineda et al. · Neuron · 2020 · 93 citations · Full text

Life Sciences, Neurobiology, Neuroscience +12

A partnership between the lipid scramblase XK and the lipid transfer protein VPS13A at the plasma membrane

Andrés Guillén-Samander, Yumei Wu, S. Sebastian Pineda et al. · Proceedings of the National Academy of Sciences · 2022 · 76 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Transcriptional vulnerabilities of striatal neurons in human and rodent models of Huntington’s disease

A. Matsushima, S. Sebastian Pineda, Jill R. Crittenden et al. · Nature Communications · 2023 · 69 citations · Full text

Life Sciences, Neurology, Neuroscience +16

Single-cell profiling of the human primary motor cortex in ALS and FTLD

S. Sebastian Pineda, Hyeseung Lee, Brent E. Fitzwalter et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 42 citations · Full text

Life Sciences, Neurology, Neuroscience +15