BACE1 regulates voltage-gated sodium channels and neuronal activity

Doo Yeon Kim, Bryce W. Carey, Haibin Wang, +8

Nature Cell Biology

Molecular NeuroscienceHyperpolarization (Biology)NeurophysiologyPhysiologyIon Channels +6

Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits

Bikem Akten, Min Jeong Kye, Le Hao, +9

Proceedings of the National Academy of Sciences

NeurogenomicsCytoskeletonCellular NeurobiologySynaptic SignalingSocial Sciences +24

SMN regulates axonal local translation via miR-183/mTOR pathway

Min Jeong Kye, Emily Niederst, Mary H. Wertz, +11

Human Molecular Genetics

Neurodegenerative DiseasesMolecular NeuroscienceSmn ProteinAxonal Local TranslationSpinal Muscular Atrophy +9

Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1

Alessia Di Nardo, Mary H. Wertz, Erica Kwiatkowski, +9

Human Molecular Genetics

MitophagyAutophagy ActivationCytoskeletonCellular PhysiologyTuberous Sclerosis Complex +15

Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity

Mary H. Wertz, Mollie R. Mitchem, S. Sebastian Pineda, +16

Neuron

NeuroprotectionNeurologyNeuroscienceNeurodegenerationMolecular Neurobiology +4

Cell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophy

Mary H. Wertz, Kellen D. Winden, Pierre Neveu, +3

Human Molecular Genetics

Interleukin-6 deficiency exacerbates Huntington’s disease model phenotypes

Mary H. Wertz, S. Sebastian Pineda, Hyeseung Lee, +3

Molecular Neurodegeneration

Divergent dysregulation of gene expression in murine models of fragile X syndrome and tuberous sclerosis

Sek Won Kong, Mustafa Şahin, Christin Collins, +7

Molecular Autism

Characterization of the nuclear localization signal of high risk HPV16 E2 protein

Kristin M. Klucevsek, Mary H. Wertz, John Lucchi, +2

Virology

Virus StructureMedicineNuclear Localization SignalNatural SciencesMolecular Biology +4

Shape deformation analysis reveals the temporal dynamics of cell-type-specific homeostatic and pathogenic responses to mutant huntingtin

Lucile Mégret, Barbara Gris, Satish S. Nair, +8

eLife