Paarth B. Dodhiawala

IRAK4 Signaling Drives Resistance to Checkpoint Immunotherapy in Pancreatic Ductal Adenocarcinoma

Vikas Somani, Daoxiang Zhang, Paarth B. Dodhiawala et al. · Gastroenterology · 2022 · 59 citations · Full text

Pancreatic Cancer, Medicine, Receptor Tyrosine Kinase +10

Concurrent HER or PI3K Inhibition Potentiates the Antitumor Effect of the ERK Inhibitor Ulixertinib in Preclinical Pancreatic Cancer Models

Hongmei Jiang, Lin Li, Patrick Grierson et al. · Molecular Cancer Therapeutics · 2018 · 41 citations · Full text

Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapy

Chong Zuo, John Baer, Brett L. Knolhoff et al. · The Journal of Experimental Medicine · 2023 · 40 citations · Full text

Tumor-associated Macrophages, Tam Proliferation, Immunology +19

TPL2 enforces RAS-induced inflammatory signaling and is activated by point mutations

Paarth B. Dodhiawala, Namrata Khurana, Daoxiang Zhang et al. · Journal of Clinical Investigation · 2020 · 30 citations · Full text

T-regulatory Cell, Immunology, Immune Regulation +22

Combined KRAS-MAPK pathway inhibitors and HER2-directed drug conjugate is efficacious in pancreatic cancer

Ashenafi Bulle, Peng Liu, Kuljeet Seehra et al. · Nature Communications · 2024 · 21 citations · Full text