Jordan P. Volpato

Multiple Conformers in Active Site of Human Dihydrofolate Reductase F31R/Q35E Double Mutant Suggest Structural Basis for Methotrexate Resistance

Jordan P. Volpato, Brahm J. Yachnin, Jonathan Blanchet et al. · Journal of Biological Chemistry · 2009 · 46 citations · Full text

Increasing Methotrexate Resistance by Combination of Active-site Mutations in Human Dihydrofolate Reductase

Jordan P. Volpato, Elena Fossati, Joelle N. Pelletier · Journal of Molecular Biology · 2007 · 41 citations

Reductive Stress, Methotrexate Resistance, Biochemistry +10

Combinatorial active‐site variants confer sustained clavulanate resistance in <scp>B</scp>laC β‐lactamase from <scp><i>M</i></scp><i>ycobacterium tuberculosis</i>

Philippe Egesborg, Hélène Carlettini, Jordan P. Volpato et al. · Protein Science · 2014 · 18 citations · Full text

Microbial Pathogens, Double Variants, Bacteriology +27

2-Tier Bacterial and In Vitro Selection of Active and Methotrexate-Resistant Variants of Human Dihydrofolate Reductase

Elena Fossati, Jordan P. Volpato, Lucie Poulin et al. · SLAS DISCOVERY · 2008 · 15 citations · Full text

Novel crystallization conditions for tandem variant R67 DHFR yield a wild-type crystal structure

Brahm J. Yachnin, Damien Y. Colin, Jordan P. Volpato et al. · Acta Crystallographica Section F Structural Biology and Crystallization Communications · 2011 · 11 citations · Full text