Elena Fossati

Reconstitution of a 10-gene pathway for synthesis of the plant alkaloid dihydrosanguinarine in Saccharomyces cerevisiae

Elena Fossati, Andrew Ekins, Lauren Narcross et al. · Nature Communications · 2014 · 186 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Synthesis of Morphinan Alkaloids in Saccharomyces cerevisiae

Elena Fossati, Lauren Narcross, Andrew Ekins et al. · PLoS ONE · 2015 · 114 citations · Full text

Medicine, Biotechnology, Pharmacology +17

Characterization of a Flavoprotein Oxidase from Opium Poppy Catalyzing the Final Steps in Sanguinarine and Papaverine Biosynthesis

Jillian M. Hagel, Guillaume A.W. Beaudoin, Elena Fossati et al. · Journal of Biological Chemistry · 2012 · 69 citations · Full text

Life Sciences, Biochemistry, Enzymology +7

Multiple Conformers in Active Site of Human Dihydrofolate Reductase F31R/Q35E Double Mutant Suggest Structural Basis for Methotrexate Resistance

Jordan P. Volpato, Brahm J. Yachnin, Jonathan Blanchet et al. · Journal of Biological Chemistry · 2009 · 48 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Increasing Methotrexate Resistance by Combination of Active-site Mutations in Human Dihydrofolate Reductase

Jordan P. Volpato, Elena Fossati, Joelle N. Pelletier · Journal of Molecular Biology · 2007 · 46 citations

Life Sciences, Biochemistry, Pharmacology +12