Linda O′Flaherty

Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling

Julie Adam, Emine Hatipoglu, Linda O′Flaherty et al. · Cancer Cell · 2011 · 578 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Aberrant succination of proteins in fumarate hydratase‐deficient mice and HLRCC patients is a robust biomarker of mutation status

Chiara Bardella, Mona El‐Bahrawy, Norma Frizzell et al. · The Journal of Pathology · 2011 · 279 citations

Medicine, Biochemistry, Oncology +17

Inhibition of Mitochondrial Aconitase by Succination in Fumarate Hydratase Deficiency

Nicola Ternette, Ming Yang, Mahima Laroyia et al. · Cell Reports · 2013 · 158 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)

Armin Thalhammer, Zuzana Bencokova, Rachel L. Poole et al. · PLoS ONE · 2011 · 153 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Determination of PD-L1 Expression in Circulating Tumor Cells of NSCLC Patients and Correlation with Response to PD-1/PD-L1 Inhibitors

Melanie Janning, Franca Kobus, Anna Babayan et al. · Cancers · 2019 · 138 citations · Full text

Medicine, Cancer Biology, Oncology +17