David Fox

Structural basis for RNA replication by the hepatitis C virus polymerase

T.C. Appleby, Jason K. Perry, Eisuke Murakami et al. · Science · 2015 · 352 citations

Life Sciences, Biology, Molecular Biology +17

Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex

Peter S. Brzović, Jennifer R. Keeffe, Hiroyuki Nishikawa et al. · Proceedings of the National Academy of Sciences · 2003 · 349 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +17

Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation

Dongyi Xu, Weiping Shen, Rong Guo et al. · Nature Neuroscience · 2013 · 149 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +15

Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer

James P. O’Connell, John Porter, Boris Kroeplien et al. · Nature Communications · 2019 · 131 citations · Full text

Medicine, Immunology, Pharmacology +12

Increasing the structural coverage of tuberculosis drug targets

Loren Baugh, Isabelle Phan, Darren W. Begley et al. · Tuberculosis · 2014 · 130 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13