Sophia W.M. Bruggeman

Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

Daan Peric‐Hupkes, Wouter Meuleman, Ludo Pagie et al. · Molecular Cell · 2010 · 1.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

<i>Ink4a</i> and <i>Arf</i> differentially affect cell proliferation and neural stem cell self-renewal in <i>Bmi1</i>-deficient mice

Sophia W.M. Bruggeman, Merel E. Valk-Lingbeek, Petra P.M. van der Stoop et al. · Genes & Development · 2005 · 312 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Bmi1 Controls Tumor Development in an Ink4a/Arf-Independent Manner in a Mouse Model for Glioma

Sophia W.M. Bruggeman, Danielle Hulsman, Ellen Tanger et al. · Cancer Cell · 2007 · 291 citations · Full text

Medicine, Genetics, Oncology +11

Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation

Karin Klauke, Višnja Radulović, Mathilde Broekhuis et al. · Nature Cell Biology · 2013 · 233 citations

Life Sciences, Cell Biology, Genetics +13

In Vivo RNAi Screen for BMI1 Targets Identifies TGF-β/BMP-ER Stress Pathways as Key Regulators of Neural- and Malignant Glioma-Stem Cell Homeostasis

Gaetano Gargiulo, Matteo Cesaroni, Michela Serresi et al. · Cancer Cell · 2013 · 182 citations · Full text

Life Sciences, Neuroscience, Oncology +16