In Vivo RNAi Screen for BMI1 Targets Identifies TGF-β/BMP-ER Stress Pathways as Key Regulators of Neural- and Malignant Glioma-Stem Cell Homeostasis

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Roel G.W. Verhaak, Katherine A. Hoadley, Elizabeth Purdom et al. · Cancer Cell · 2010 · 7.5K citations · Full text

Neuro-oncology, Oncology, Tumor Heterogeneity +13

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

John D. Cahoy, Ben Emery, Amit Kaushal et al. · Journal of Neuroscience · 2008 · 3.1K citations · Full text

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

Anna V. Molofsky, Ricardo Pardal, Toshihide Iwashita et al. · Nature · 2003 · 1.3K citations · Full text

Progenitor Cells, Developmental Biology, Molecular Neuroscience +11

The transcriptional network for mesenchymal transformation of brain tumours

Maria Stella Carro, Wei Keat Lim, Mariano J. Alvarez et al. · Nature · 2009 · 1.3K citations · Full text

Neuro-oncology, Transcriptional Network, Glioma +5

Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

Yeshayahu Schlesinger, Ravid Straussman, Ilana Keshet et al. · Nature Genetics · 2006 · 1.2K citations

Histone Modifications, Chromatin, Polycomb-mediated Methylation +12