Christian J. Leumann

Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers

Aurélie Goyenvalle, Graziella Griffith, Arran Babbs et al. · Nature Medicine · 2015 · 306 citations

Chromatin, Genome Instability, Exon-skipping Tricyclo-dna Oligomers +8

A new strategy for the generation of catalytic antibodies

Kevan M. Shokat, Christian J. Leumann, Renee Sugasawara et al. · Nature · 1989 · 164 citations

Engineering, Biochemistry, Natural Sciences +7

Oxidative stress damages rRNA inside the ribosome and differentially affects the catalytic center

Jessica Willi, Pascal A. Küpfer, Damien Evéquoz et al. · Nucleic Acids Research · 2017 · 142 citations · Full text

Ribosomal Rna, Molecular Biology, Reactive Oxygen Species +17

Warum pentose‐und nicht hexose‐nucleinsäuren? Teil III. Oligo(2′,3′‐dideoxy‐β‐<scp>D</scp>‐glucopyranosyl) nucleotide (‘homo‐DNS’): Paarungesigenschaften

Jürg Hunziker, Hans‐Jörg Roth, Markus Böhringer et al. · Helvetica Chimica Acta · 1993 · 138 citations

Nucleic Acid Chemistry, Bioorganic Chemistry, Biochemistry +12

Nucleic‐Acid Analogues with Constraint Conformational Flexibility in the Sugar‐Phosphate Backbone (‘Bicyclo‐DNA’). Part 1. Preparation of (3<i>S</i>,5′<i>R</i>)‐2′‐Deoxy‐3′,5′‐ethano‐αβ‐<scp>D</scp>‐ribonucleosides (‘Bicyclonucleosides’)

Markus Tarköy, Martin H. Bolli, W. Bernd Schweizer et al. · Helvetica Chimica Acta · 1993 · 128 citations

Nucleic Acid Chemistry, Bioorganic Chemistry, Dna +15