Hemali Amunugama

Polymorphic Variants of Cytochrome P450 2B6 (CYP2B6.4–CYP2B6.9) Exhibit Altered Rates of Metabolism for Bupropion and Efavirenz: A Charge-Reversal Mutation in the K139E Variant (CYP2B6.8) Impairs Formation of a Functional Cytochrome P450-Reductase Complex

Haoming Zhang, Chitra Sridar, Cesar Kenaan et al. · Journal of Pharmacology and Experimental Therapeutics · 2011 · 63 citations · Full text

Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Clopidogrel: Involvement of Both Covalent Modification of Cysteinyl Residue 475 and Loss of Heme

Haoming Zhang, Hemali Amunugama, Sarah Ney et al. · Molecular Pharmacology · 2011 · 41 citations · Full text

Mechanism-Based Inactivation of Cytochrome P450 2B6 by Methadone through Destruction of Prosthetic Heme

Hemali Amunugama, Haoming Zhang, Paul F. Hollenberg · Drug Metabolism and Disposition · 2012 · 19 citations · Full text