Cesar Kenaan - Concepedia

Author

Cesar Kenaan

University of Michigan

Also Known As

Cesar Kenaan, Kenaan, Cesar

Publications

361

Citations

H-Index

Concepts

All Affiliations

University of Michigan Regional West Medical Center

About

Cesar Kenaan is an author at University of Michigan specializing in medicine, biochemistry, and chemical biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	4	4	94
2	Biochemistry	4	4	94
3	Natural Sciences	3	3	80
4	Chemical Biology	3	3	80
5	Metabolism	1	1	23

Cesar Kenaan

Publications

332

Citations

H-Index

Page 1

	Year	Citations
Polymorphic Variants of Cytochrome P450 2B6 (CYP2B6.4–CYP2B6.9) Exhibit Altered Rates of Metabolism for Bupropion and Efavirenz: A Charge-Reversal Mutation in the K139E Variant (CYP2B6.8) Impairs Formation of a Functional Cytochrome P450-Reductase Complex Haoming Zhang, Chitra Sridar, Cesar Kenaan, Journal of Pharmacology and Experimental Therapeutics	2011	63
Identification of the Residue in Human CYP3A4 That Is Covalently Modified by Bergamottin and the Reactive Intermediate That Contributes to the Grapefruit Juice Effect Hsia-lien Lin, Cesar Kenaan, Paul F. Hollenberg Drug Metabolism and Disposition	2012	61
Uncovering the Role of Hydrophobic Residues in Cytochrome P450−Cytochrome P450 Reductase Interactions Cesar Kenaan, Haoming Zhang, Erin V. Shea, Biochemistry	2011	45
Effect of Conformational Dynamics on Substrate Recognition and Specificity as Probed by the Introduction of a de Novo Disulfide Bond into Cytochrome P450 2B1 Haoming Zhang, Cesar Kenaan, Djemel Hamdane, Journal of Biological Chemistry Conformational DynamicsProtein AssemblyBiomolecular Structure PredictionMolecular BiologyChemical Biology	2009	33
Inhibition of Bupropion Metabolism by Selegiline: Mechanism-Based Inactivation of Human CYP2B6 and Characterization of Glutathione and Peptide Adducts Chitra Sridar, Cesar Kenaan, Paul F. Hollenberg Drug Metabolism and Disposition	2012	27
The Effect of Ritonavir on Human CYP2B6 Catalytic Activity: Heme Modification Contributes to the Mechanism-Based Inactivation of CYP2B6 and CYP3A4 by Ritonavir Hsia-lien Lin, Jaime D’Agostino, Cesar Kenaan, Drug Metabolism and Disposition	2013	25
Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Chlorpyrifos Jaime D’Agostino, Haoming Zhang, Cesar Kenaan, Chemical Research in Toxicology Pesticide-residue AnalysisChemical ControlChemical BiologyToxicological MechanismInactivated Cyp2b6	2015	24
Reaction of Human Cytochrome P450 3A4 with Peroxynitrite: Nitrotyrosine Formation on the Proximal Side Impairs Its Interaction with NADPH-Cytochrome P450 Reductase Hsia-lien Lin, Cesar Kenaan, Haoming Zhang, Chemical Research in Toxicology Lipid PeroxidationNadph-cytochrome P450 ReductaseChemical BiologyRedox BiologyOxidative Stress	2012	23
Interactions between CYP2E1 and CYP2B4: Effects on Affinity for NADPH-Cytochrome P450 Reductase and Substrate Metabolism Cesar Kenaan, Erin V. Shea, Hsia-lien Lin, Drug Metabolism and Disposition	2012	17
A quantitative high-throughput 96-well plate fluorescence assay for mechanism-based inactivators of cytochromes P450 exemplified using CYP2B6 Cesar Kenaan, Haoming Zhang, Paul F. Hollenberg Nature Protocols BiochemistryMedicineMechanism-based InactivatorsBioanalysisCytochromes P450	2010	14

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