Edward F. Elslager

Antimalarial substances. 26. Folate antagonists. 4. Antimalarial and antimetabolite effects of 2,4-diamino-6-[(benzyl)amino]pyrido[2,3-d]pyrimidines

John Davoll, J. Clarke, Edward F. Elslager · Journal of Medicinal Chemistry · 1972 · 101 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Anthrapyrazole anticancer agents. Synthesis and structure-activity relationships against murine leukemias

H. D. Hollis Showalter, Judith L. Johnson, Jeanne M. Hoftiezer et al. · Journal of Medicinal Chemistry · 1987 · 99 citations

Medicine, Oncology, Pharmacology +8

Biochemical pharmacology of the lipophilic antifolate, trimetrexate

Robert Jackson, David W. Fry, Theodore J. Boritzki et al. · Advances in Enzyme Regulation · 1984 · 94 citations

Medicine, Medicinal Chemistry, Pharmacology +7

Folate antagonists. 20. Synthesis and antitumor and antimalarial properties of trimetrexate and related 6-[(phenylamino)methyl]-2,4-quinazolinediamines

Edward F. Elslager, Judith L. Johnson, Leslie M. Werbel · Journal of Medicinal Chemistry · 1983 · 80 citations

Medicine, Medicinal Chemistry, Pharmacology +10

2,4-Diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline (TMQ), a potent non-classical folate antagonist inhibitor—I

Joseph R. Bertino, Wendy L. Sawicki, Barbara A. Moroson et al. · Biochemical Pharmacology · 1979 · 79 citations

Medicine, Medicinal Chemistry, Pharmacology +5