Jack Pollard

Causal analysis approaches in Ingenuity Pathway Analysis

A. Krämer, Jeff Green, Jack Pollard et al. · Bioinformatics · 2013 · 5.9K citations · Full text

Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models

C. Hotz, Timothy R. Wagenaar, Friederike Gieseke et al. · Science Translational Medicine · 2021 · 187 citations

Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition

Michael Lampa, Heike Arlt, Timothy He et al. · PLoS ONE · 2017 · 156 citations · Full text

Breast Oncology, Tumor Cells, Metabolic Remodeling +18

Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers

Malvika Koundinya, Judith Sudhalter, Albane Courjaud et al. · Cell chemical biology · 2018 · 118 citations

Biosynthesis, Biochemistry, Natural Sciences +5

T-cell Responses to Individualized Neoantigen Therapy mRNA-4157 (V940) Alone or in Combination with Pembrolizumab in the Phase 1 KEYNOTE-603 Study

Justin F. Gainor, Manish R. Patel, Jeffrey S. Weber et al. · Cancer Discovery · 2024 · 77 citations