Helena Kempski

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

Steven J. Howe, Marc R. Mansour, Kerstin Schwarzwaelder et al. · Journal of Clinical Investigation · 2008 · 1.3K citations · Full text

Genetic variegation of clonal architecture and propagating cells in leukaemia

Kristina Anderson, Christoph Lutz, Frederik W. van Delft et al. · Nature · 2010 · 799 citations

Cell Division, Cytogenetics, Mixed-phenotype Acute Leukemia +7

RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia

Elli Papaemmanuil, Inmaculada Rapado, Yilong Li et al. · Nature Genetics · 2014 · 374 citations · Full text

Hematological Malignancy, Rag-mediated Recombination, Oncogenic Rearrangement +7

Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group

Libi Hertzberg, Elena Vendramini, Ithamar Ganmore et al. · Blood · 2009 · 344 citations · Full text

Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome

Dani Bercovich, Ithamar Ganmore, Linda M. Scott et al. · The Lancet · 2008 · 336 citations

Down Syndrome, Hematological Malignancy, Acute Lymphoblastic Leukaemias +10