Somatic<i>SF3B1</i>Mutation in Myelodysplasia with Ring Sideroblasts

Elli Papaemmanuil, Mario Cazzola, Jacqueline Boultwood, +45

New England Journal of Medicine

Identification of Flt3+ Lympho-Myeloid Stem Cells Lacking Erythro-Megakaryocytic Potential

Jörgen Adolfsson, Robert Månsson, Natalija Buza-Vidas, +12

Cell

Developmental BiologyMedicineHematologyMyeloid NeoplasiaBlood Cell +5

Genetic variegation of clonal architecture and propagating cells in leukaemia

Kristina Anderson, Christoph Lutz, Frederik W. van Delft, +9

Nature

Cell DivisionCytogeneticsMixed-phenotype Acute LeukemiaGeneticsMolecular Genetics +5

Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block

Peggy Kirstetter, Kristina Anderson, Bo Porse, +2

Nature Immunology

Canonical Wnt PathwayDevelopmental BiologyMedicineAdult Stem CellStem Cell Research +4

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia

Alice Giustacchini, Supat Thongjuea, Nikolaos Barkas, +17

Nature Medicine

Single-cell Transcriptomics UncoversChronic Myeloid LeukemiaSingle Cell SequencingMedicineGenetics +11

IL-6 triggers cell growth via the Ras-dependent mitogen-activated protein kinase cascade

Atsushi Ogata, Dharminder Chauhan, Gerrard Teoh, +4

The Journal of Immunology

Molecular Evidence for Hierarchical Transcriptional Lineage Priming in Fetal and Adult Stem Cells and Multipotent Progenitors

Robert Månsson, Anne Hultquist, Sidinh Luc, +13

Immunity

Multipotent ProgenitorsEmbryonic Stem CellCell LineageLineage PlasticityDevelopmental Biology +10

Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia

Anders Castor, Lars Nilsson, Ingbritt Åstrand‐Grundström, +13

Nature Medicine

Hematological MalignancyDistinct PatternsMedicineStem Cell MobilizationMixed-phenotype Acute Leukemia +8

Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo

Petter Woll, Una Kjällquist, Onima Chowdhury, +45

Cancer Cell

Hematological MalignancyBone Marrow FailureMyelodysplastic SyndromesMedicineMyeloid Neoplasia +7

Persistent Malignant Stem Cells in del(5q) Myelodysplasia in Remission

Ramin Tehranchi, Petter Woll, Kristina Anderson, +18

New England Journal of Medicine