Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group

Libi Hertzberg, Elena Vendramini, Ithamar Ganmore, +21

Blood

Poor prognosis for P2RY8-CRLF2 fusion but not for CRLF2 over-expression in children with intermediate risk B-cell precursor acute lymphoblastic leukemia

Chiara Palmi, Elena Vendramini, Daniela Silvestri, +19

Leukemia

Hematological MalignancyMedicineMixed-phenotype Acute LeukemiaHematologyPathology +7

Early Relapse in ALL Is Identified by Time to Leukemia in NOD/SCID Mice and Is Characterized by a Gene Signature Involving Survival Pathways

Lüder Hinrich Meyer, Sarah M. Eckhoff, Manon Queudeville, +16

Cancer Cell

Hematological MalignancyNod/scid MiceAll IsMedicineMixed-phenotype Acute Leukemia +9

MicroRNA-486-5p is an erythroid oncomiR of the myeloid leukemias of Down syndrome

Lital Shaham, Elena Vendramini, Yubin Ge, +16

Blood

NOTCH1-mutated chronic lymphocytic leukemia cells are characterized by a MYC-related overexpression of nucleophosmin 1 and ribosome-associated components

Federico Pozzo, Tamara Bittolo, Elena Vendramini, +15

Leukemia

Hematological MalignancyChromatinNucleophosmin 1Myc-related OverexpressionImmunology +6

<i>TP53</i> Mutations with Low Variant Allele Frequency Predict Short Survival in Chronic Lymphocytic Leukemia

Riccardo Bomben, Francesca Maria Rossi, Filippo Vit, +34

Clinical Cancer Research

Treatment outcome of <scp><i>CRLF2</i></scp>‐rearranged childhood acute lymphoblastic leukaemia: a comparative analysis of the <scp>AIEOP</scp>‐<scp>BFM</scp> and <scp>UK NCRI</scp>‐<scp>CCLG</scp> study groups

Andishe Attarbaschi, Maria Morak, Gunnar Cario, +20

British Journal of Haematology

High expression of miR-125b-2 and SNORD116 noncoding RNA clusters characterize ERG-related B cell precursor acute lymphoblastic leukemia

Elena Vendramini, Marco Giordan, Emanuela Giarin, +11

Oncotarget

PAX5 fusion genes are frequent in poor risk childhood acute lymphoblastic leukaemia and can be targeted with BIBF1120

Grazia Fazio, Silvia Bresolin, Daniela Silvestri, +24

EBioMedicine

&lt;i&gt;SF3B1&lt;/i&gt;-mutated chronic lymphocytic leukemia shows evidence of NOTCH1 pathway activation including CD20 downregulation

Federico Pozzo, Tamara Bittolo, Erika Tissino, +15

Haematologica

Chronic Lymphocytic LeukemiaMixed-phenotype Acute LeukemiaImmunologyCd20 DownregulationCll Subset +15