Federico M. Ruiz

Crystal structure of the 14-subunit RNA polymerase I

Carlos Fernández‐Tornero, M. Moreno-Morcillo, Umar Rashid et al. · Nature · 2013 · 198 citations · Full text

Crystal Structure, Viral Polymerase Structure, Protein X-ray Crystallography +3

Aldose reductase structures: implications for mechanism and inhibition

Ossama El‐Kabbani, Federico M. Ruiz, Connie Darmanin et al. · Cellular and Molecular Life Sciences · 2004 · 114 citations · Full text

Biosynthesis, Aldo-keto Reductase, Cellular Enzymology +6

The Binding of Triclosan to SmeT, the Repressor of the Multidrug Efflux Pump SmeDEF, Induces Antibiotic Resistance in Stenotrophomonas maltophilia

Alvaro G. Hernandez, Federico M. Ruiz, Antonio Romero et al. · PLoS Pathogens · 2011 · 108 citations · Full text

Antimicrobial Chemotherapy, Antibiotic Resistance, Drug Resistance +17

Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with fidarestat and minalrestat: Implications for the binding of cyclic imide inhibitors

Ossama El‐Kabbani, Connie Darmanin, T. Schneider et al. · Proteins Structure Function and Bioinformatics · 2004 · 93 citations · Full text

Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase

Matthew P. Blakeley, Federico M. Ruiz, Raúl E. Cachau et al. · Proceedings of the National Academy of Sciences · 2008 · 80 citations · Full text

Engineering, Aldo-keto Reductase, Hydrogen Bond Network +21