Connie Darmanin

Megahertz serial crystallography

Max O. Wiedorn, Dominik Oberthür, Richard Bean et al. · Nature Communications · 2018 · 200 citations · Full text

Aldose reductase structures: implications for mechanism and inhibition

Ossama El‐Kabbani, Federico M. Ruiz, Connie Darmanin et al. · Cellular and Molecular Life Sciences · 2004 · 114 citations · Full text

Biosynthesis, Aldo-keto Reductase, Cellular Enzymology +6

MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography

Max T. B. Clabbers, Susannah Holmes, Timothy W. Muusse et al. · Nature Communications · 2021 · 95 citations · Full text

Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with fidarestat and minalrestat: Implications for the binding of cyclic imide inhibitors

Ossama El‐Kabbani, Connie Darmanin, T. Schneider et al. · Proteins Structure Function and Bioinformatics · 2004 · 93 citations · Full text

Structure of Aldehyde Reductase Holoenzyme in Complex with the Potent Aldose Reductase Inhibitor Fidarestat:  Implications for Inhibitor Binding and Selectivity

Ossama El‐Kabbani, Vincenzo Carbone, Connie Darmanin et al. · Journal of Medicinal Chemistry · 2005 · 73 citations · Full text

Aldo-keto Reductase, Molecular Biology, Inhibitory Activity Measurements +17