Sondra L. Downey-Kopyscinski

Selective Inhibitor of Proteasome's Caspase-like Sites Sensitizes Cells to Specific Inhibition of Chymotrypsin-like Sites

Matthew Britton, Marcella M. Lucas, Sondra L. Downey-Kopyscinski et al. · Chemistry & Biology · 2009 · 162 citations · Full text

Specific Inhibition, Protein Function, Signal Transduction +11

Specific Cell-Permeable Inhibitor of Proteasome Trypsin-like Sites Selectively Sensitizes Myeloma Cells to Bortezomib and Carfilzomib

Anne Mirabella, Alexandre A. Pletnev, Sondra L. Downey-Kopyscinski et al. · Chemistry & Biology · 2011 · 105 citations

Protein Function, Medicine, Immunology +5

Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins

Ryosuke Shirasaki, Geoffrey M. Matthews, Sara Gandolfi et al. · Cell Reports · 2021 · 105 citations · Full text

Molecular Basis of Differential Sensitivity of Myeloma Cells to Clinically Relevant Bolus Treatment with Bortezomib

Tamer B. Shabaneh, Sondra L. Downey-Kopyscinski, Ayrton L. Goddard et al. · PLoS ONE · 2013 · 63 citations · Full text

Proteasome Inhibitors, Immunology, Proteasome Inhibitor Bortezomib +21

Nature of Pharmacophore Influences Active Site Specificity of Proteasome Inhibitors

Michael Screen, Matthew Britton, Sondra L. Downey-Kopyscinski et al. · Journal of Biological Chemistry · 2010 · 60 citations · Full text