Anne Mirabella

Genome-wide reprogramming of the chromatin landscape underlies endocrine therapy resistance in breast cancer

Luca Magnani, Alexander Stoeck, Xiaoyang Zhang et al. · Proceedings of the National Academy of Sciences · 2013 · 185 citations · Full text

Medicine, Genetics, Oncology +17

Specific Cell-Permeable Inhibitor of Proteasome Trypsin-like Sites Selectively Sensitizes Myeloma Cells to Bortezomib and Carfilzomib

Anne Mirabella, Alexandre A. Pletnev, Sondra L. Downey-Kopyscinski et al. · Chemistry & Biology · 2011 · 105 citations

Medicine, Molecular Biology, Oncology +9

Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites

Paul P. Geurink, Wouter A. van der Linden, Anne Mirabella et al. · Journal of Medicinal Chemistry · 2013 · 94 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

The novel  2-selective proteasome inhibitor LU-102 synergizes with bortezomib and carfilzomib to overcome proteasome inhibitor resistance of myeloma cells

Marianne Kraus, Jürgen Bader, Paul P. Geurink et al. · Haematologica · 2015 · 49 citations · Full text

Medicine, Oncology, Pharmacology +13