Oxana Polyakova

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

Huw D. Lewis, John Liddle, Jim Coote et al. · Nature Chemical Biology · 2015 · 760 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +2

The γδTCR combines innate immunity with adaptive immunity by utilizing spatially distinct regions for agonist selection and antigen responsiveness

Daisy Melandri, Iva Zlatareva, Raphaël A. G. Chaleil et al. · Nature Immunology · 2018 · 231 citations · Full text

Life Sciences, Immunology, Adaptive Immunity +12

Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function

Olga V. Moroz, Will Burkitt, Helmut Wittkowski et al. · BMC Biochemistry · 2009 · 119 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Discovery of Novel Irreversible Inhibitors of Interleukin (IL)-2-inducible Tyrosine Kinase (Itk) by Targeting Cysteine 442 in the ATP Pocket

John D. Harling, Angela M. Deakin, Sébastien Campos et al. · Journal of Biological Chemistry · 2013 · 34 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Over Expression of Wild Type or a Catalytically Dead Mutant of SIRTUIN 6 Does Not Influence NFκB Responses

Rachel L. Grimley, Oxana Polyakova, Jessica Vamathevan et al. · PLoS ONE · 2012 · 30 citations · Full text

Life Sciences, Genetics, Molecular Biology +15