Brandy Strake

Three-Dimensional Lung Tumor Microenvironment Modulates Therapeutic Compound Responsiveness In Vitro – Implication for Drug Development

Jason E. Ekert, Kjell Johnson, Brandy Strake et al. · PLoS ONE · 2014 · 172 citations · Full text

Engineering, Lung Inflammation, Cmet Receptor Expression +20

An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations

Omid Vafa, Gary L. Gilliland, Randall J. Brezski et al. · Methods · 2013 · 149 citations

Engineered Fc Variant, Signal Transduction, Autoimmune Disease +12

Anti-leukemic activity and tolerability of anti-human CD47 monoclonal antibodies

E. Christine Pietsch, Jianying Dong, Rosa Cardoso et al. · Blood Cancer Journal · 2017 · 111 citations · Full text

The in vitro resistance of IgG2 to proteolytic attack concurs with a comparative paucity of autoantibodies against peptide analogs of the IgG2 hinge

Randall J. Brezski, Allison Oberholtzer, Brandy Strake et al. · mAbs · 2011 · 38 citations · Full text

Immunology, Mammalian Antibody Repertoire, Antigen Processing +17

Coevolution of Antibody Stability and Vκ CDR-L3 Canonical Structure

Jinquan Luo, Galina Obmolova, Alice H. Huang et al. · Journal of Molecular Biology · 2010 · 23 citations

Immunology, Immunodominance, Antigen Processing +5