Concepedia

Randall J. Brezski

RJ

Statistics

Publications

26

Citations

2.1K

H-Index

20

Active since

2005

Affiliations

Janssen (United States)(Current)

Springhouse

Janssen (Belgium)

Brown Foundation

University of Pennsylvania

Randall J. Brezski is an author at Janssen (United States) specializing in immunology, antibody characterization, and antibody engineering.

ORCID

Publications per year

2005–2023

26

Publications

26

Effector-attenuating Substitutions That Maintain Antibody Stability and Reduce Toxicity in Mice

Megan Lo, Hok Seon Kim, Raymond K. Tong et al. · Journal of Biological Chemistry · 2017 · 330 citations · Full text

, , +16

A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor–Resistant Lung Tumors

Sheri L. Moores, Mark L. Chiu, Barbara S. Bushey et al. · Cancer Research · 2016 · 283 citations

, , +17

Tonic B cell antigen receptor signals supply an NF-κB substrate for prosurvival BLyS signaling

Jason Stadanlick, Mary Kaileh, Fredrick G. Karnell et al. · Nature Immunology · 2008 · 204 citations · Full text

, , +14

Trastuzumab Triggers Phagocytic Killing of High HER2 Cancer Cells In Vitro and In Vivo by Interaction with Fcγ Receptors on Macrophages

Yun Shi, Xuejun Fan, Hui Deng et al. · The Journal of Immunology · 2015 · 190 citations

, , +16

An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations

Omid Vafa, Gary L. Gilliland, Randall J. Brezski et al. · Methods · 2013 · 149 citations

, , +16

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